From Blacksburg:  Head southeast on N. Main St. toward Roanoke St. E. Take the ramp to US-460 E/I-81/Roanoke. Merge onto US-460 E. Take exit 4A-4B toward VA-114 E. Turn left onto Peppers Ferry Rd. Peppers Ferry Rd. turns left and becomes Cinnabar Rd. The Animal Shelter will be on the right.

From Christiansburg:  Head northwest on US-460 BUS W/N Franklin St. toward Commerce St. NW. Continue to follow US-460 BUS W. Turn right onto Peppers Ferry Rd. Peppers Ferry Rd. turns left and becomes Cinnabar Rd. The Animal Shelter will be on the right.

From Radford:  Head northwest on Berkley St. toward 2nd St. Take third right onto 1st St./W. Main St. Continue to follow W. Main St. Continue onto US-11 N. Turn left onto W. Main St. Turn left onto US-460 BUS W/N Franklin St. Continue to follow US-460 BUS W. Turn right onto Peppers Ferry Rd. Peppers Ferry Rd. turns left and becomes Cinnabar Rd. The Animal Shelter will be on the right.